KI-ZA-SHI is a fully automated ELISA platform designed to measure ultra–trace biomarkers in blood with high sensitivity and reproducibility.
By automating the entire measurement workflow, the system minimizes operator-dependent variability and enables stable, reliable data acquisition.

• Fully automated measurement (integrated control of dispensing, reaction, washing, and detection)
• Capability to measure ultra‑trace analytes
• Reproducibility-focused system design
• Architecture optimized for continuous operation
• Integrated design with dedicated reagent kits

This system is intended primarily for research use and aims to standardize blood biomarker measurement.
 

We are currently expanding support for the following biomarkers:

• pTau217
• mid-pTau181
•  Additional biomarkers under development

These biomarkers represent molecular targets that are gaining significant global attention in dementia‑related research.

Automation of dispensing, reaction, washing, and detection reduces operator-dependent variability.

Control architecture optimized for long-term operation ensures a stable measurement environment.

The system is designed to accommodate future biomarker expansion, enabling ongoing enhancement of measurement capabilities.

KI-ZA-SHI is being validated for research use across the following dimensions:

Stability confirmed through repeated measurements of identical samples

Evaluation of detection performance in the ultra‑trace concentration ranges

Correlation studies with existing measurement methods
※Detailed data is available in our research-use documentation.
 

• Expansion of supported biomarkers
• Joint validation with external research institutions
• Operational optimization through accumulated measurement data

KI-ZA-SHI will continue to evolve as a platform aimed at standardizing blood biomarker measurement.